Some of the medications used most successfully as VEGF inhibitors include: Patients can minimize the risk of these side effects by choosing a skilled and experienced doctor to treat all of their eye conditions. Although rare, side effects may include eye pain, conjunctival hemorrhage, floaters, increased eye pressure and inflammation of the eye. Patients may experience some mild discomfort or scratchy sensations after the injection. The medication is injected directly into the eye. The eye is then cleaned with an antiseptic solution and held open with a speculum. Before the medication is injected, the eye is numbed with anesthetic eye drops to help minimize discomfort. This procedure is performed in your doctor’s office. Intraocular injections are especially effective in treating wet age-related macular degeneration, which, although less common than the dry form, accounts for more than 90% of blindness caused by the disease. Many patients often see an improvement in their vision from these injections as well. These abnormal blood vessels will rupture and bleed, often causing severe vision loss.įDA-approved medications are injected directly into the eye to help patients maintain their baseline vision and keep vision loss at a minimum. VEGF causes fragile, abnormal blood vessels to grow inside the eye. In response to this, abnormal production of a blood vessel hormone called vascular endothelial growth factor (VEGF) takes place. These conditions cause damage to the retinal blood vessels, cutting off the supply of adequate amounts of oxygen to the retinal tissue. Intraocular injections are commonly used to treat retinal diseases such as diabetic retinopathy, macular degeneration and retinal vein occlusion.
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